Nikkei closes 375 points lower, largest fall since mid-August

TOKYO, Japan - An electronic board at a Tokyo securities firm shows the key Nikkei index falling 537.27 points shortly after noon on Oct. 22. The 225-issue Nikkei Stock Average, which lost nearly 300 points Oct. 19, rallied later in the day, closing 375.90 points lower to 16,438.47. It was the Nikkei's biggest one-day fall since it plunged 874.81 points on Aug. 17, when equities fell worldwide on uncertainties about the global financial market.