Chinese researchers make breakthrough in study for depression treatment

STORY: Chinese researchers make breakthrough in study for depression treatment DATELINE: Nov. 4, 2022 LENGTH: 00:01:25 LOCATION: NANJING, China CATEGORY: SCIENCE SHOTLIST: 1. various of Nanjing Medical University 2. various of a team of Chinese researchers from Nanjing Medical University 3. SOUNDBITE (Chinese): ZHOU QIGANG, Professor, Nanjing Medical University STORYLINE: A team of Chinese researchers from Nanjing Medical University have discovered a new antidepressant target and developed a lead compound, laying the groundwork for developing fast-onset antidepressants. The findings were published online recently in the journal Science. According to Zhou Qigang, the study's principal researcher, the serotonin transporter (SERT) is presently the primary target for anti-depressants. However, SERT inhibitors have serious limitations: they take at least 3 to 4 weeks to take effect, and they have extensive side effects. SOUNDBITE (Chinese): ZHOU QIGANG, Professor, Nanjing Medical University "We analyzed the

AUSTRALIA-NERVE PAIN-TREATMENT

AUSTRALIA-NERVE PAIN-TREATMENT

(220504) -- CANBERRA, May 4, 2022 (Xinhua) -- File photo provided by the Commonwealth Scientific and Industrial Research Organisation (CSIRO) shows a specialist pain medicine physician explaining how the brain works and its impact on pain. Australian scientists have discovered how antidepressant medications work against nerve pain, paving the way for new treatments. In a study published in the journal of RSC Medicinal Chemistry, a team from the CSIRO revealed for the first time how tricyclic antidepressants (TCAs) treat nerve pain. TO GO WITH "Australian researchers discover how antidepressants treat nerve pain" (CSIRO/Handout via Xinhua)